Nicadan®

Unique Dietary Supplement Developed by Dermatologists to Help Patients with Inflammatory Skin Conditions Maintain Healthy Skin*

Developed with:
Niacinamide

  • Demonstrates anti-inflammatory effects by blocking iodides that can lead to, or worsen, acne1
  • May reduce facial sebum production2
  • Helps improve skin barrier function by decreasing water loss3

Vitamin C

  • Demonstrates anti-inflammatory properties.4
  • Natural antioxidant slows the rate of free-radicals that damage collagen and cause skin dryness
  • May help build collagen protein in connective tissue5,6

Vitamin B6

  • Plays a vital role in proper skin function
    • Commonly deficient in patients with inflammatory skin conditions

Zinc Gluconate

  • Important to normal skin function and overall skin health
    • Deficiency may lead to a variety of inflammatory skin problems
  • Better absorbed than zinc oxide
  • Helps regenerate skin cells7

Alpha Lipoic Acid

  • Potent antioxidant that supports metabolic function
  • Helps regenerate vitamin C for further use after eradicating free radicals8

Folic Acid

  • Helps ensure proper cell function

Other Ingredients:  Microcrystalline Cellulose, Povidone, Hypromellose, Croscarmellose Sodium, Polydextrose, Talc, Magnesium Sterate Vegetable, Vegetable Stearine, Red Beet Powder, Titanium Dioxide, Maltodextrin and Triglyerides.

Nicadan® is free of yeast, wheat, dairy, egg, soy, gluten, artificial color or flavors, added sugar, starch and preservatives.

IMPORTANT SAFETY INFORMATION
If pregnant or lactating, consult your physician before taking this product. There have been reports of GI upset, nausea, vomiting, heartburn, diarrhea, dizziness, drowsiness or headache with large doses of niacinamide. Rarely, niacinamide in doses of 3 grams/day or more has been associated with elevated liver function tests.

There are case reports in the literature indicating that niacinamide may reduce the hepatic metabolism of primidone and carbamazepine. Individuals taking these medications should consult their physician. Individuals taking anti-diabetes medications should have their blood glucose levels monitored.

Please see full prescribing information

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

  1. Niren NM (2006). “Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review”. Cutis 77 (1 Suppl): 11–6. PMID 16871774.
  2. http://dermnetnz.org/treatments/nicotinamide.html
    a. Kolbach DN, Remme JJ, Bos WH, Jonkman ME, De Jong MCJM, Pas HH, Van Der Meer JB. Bullous pemphigoid successfully controlled by tetracycline and nicotinamide. Br J Dermatol 1995: 133. 88-90.
    b. Draelos ZD, Matsubara A, et al. The effect of 2% niacinamide on facial sebum production. J of Cosmetic and Laser Therapy 2006; 8: 96-101.
    c. Bissett DL, Oblong JB et al. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatol Surg 2005; 31: 860-865.
    d. Hakozaki T; Minwalla L; Zhuang J et al. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. British J. Of Dermatol 2002; 147: 20-31.
  3. Bissett DL, Miyamoto K, Sun P, et al. Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. Int J Cosmet Sci 26(5): 231-8 (2004 Oct).
  4. A. Farris PK. Topical vitamin C: a useful agent for treating photoaging and other dermatologic conditions. Dermatol Surg 2005; 31: 814-817.
  5. http://www.vitamins-supplements.org/vitamin-C.php
  6. http://www.webmd.com
  7. http://health.howstuffworks.com/skin-care/information/nutrition/zinc-benefit-skin2.htm#medlineplus
  8. http://www.vitamins-supplements.org/alpha-lipoic-acid.php

Medimetriks Pharmaceuticals, Inc.
383 Route 46 West
Fairfield, NJ 07004-2402 USA